legions of scientists and soon thereafter, by the world. This document and other documents we have recently published herald the coming of this new age of extended youth and vitality.
Before we launch into practical applications, let’s take a brief perusal of the theory. Aside from water and minerals, 95% of the flesh of all animal organisms, from single cell organisms, to sponges, to worms, to insects, to mice, and even to humans, is composed of four basic bio-chemicals: carbohydrates, fats, amino acids and nucleotides, all of which can be used
either as fuel or as cell building materials. They can either be burned as fuel to obtain energy or knitted together in combination to make huge molecules that form the structures and functions of a new cell. The universal regulatory pathway manipulates the flow of these four main constituents and the energy balance of the cell to control the maintenance of the housekeeping functions in non-dividing cells and to provide energy and material flow into the building processes to make new cells. In the past, we knew much about the flow patterns but we didn’t know how the component systems were managed. Now we do know, and we are discovering how the regulatory pathway works to control the length of our lives through its rejuvenative, regenerative and degenerative processes.
The core of the regulatory pathway sequence is called the AMPK to TOR to PGC-1alpha to ROS to SESN and back to AMPK, feedback loop. Don’t be afraid of the science jargon, it’s a simple five item list. Just think of them as the names of five people you haven’t met yet, and are just about to begin to know. Write this five-item loop down on a notepad and refer to it as you read this paper, so as